Surface Plasmon Resonance

What is SPR Nanodev offers you SPR (Surface Plasmon Resonance) systems with real-time, label free analysis options. SPR is a technique which can detect small interactions between molecules. The SPR theory is based on a physical process of light-metal film interaction. A material having a high refractive(with respect to medium) index is coated with thin gold layer. This material is treated with monochromatic light with a specific angle and some of the energy is transferred to free electron of the gold layer and forms surface plasmons. This plasmon will end up with specific refractive index. This phenomenon can be used for the biomolecule detections. Gold surface immobilized with a material. An analyte is sent through the channels and if association or dissociation happens between the immobilized material and analyte the refractive index will be changed which we can measure with high precision in real time. Where SPR technique can be used? IN SPR technique, every interaction between the molecules can be analyzed. You can find possible SPR applications below : Analysis Type Interaction Type IN SPR technique, every interaction between the molecules can be analyzed. You can find possible SPR applications below : Peptide/Protein – Protein DNA/RNA – Protein Protein – Cells Receptor- Cell Protein – Virus Carbohydrates – Protein Carbohydrates – Cell Liposome – Protein Artificial materials – biological agents Drug- Protein Drug- DNA/RNA You can use SPR technique for the analysis stated below. Analysis of affinity and avidityli> Kinetic Analysis Concentration Analysis Active Concentration Assay Analysis of the binding stoichiometry Thermodynamic Analysis Epitope Mapping Finding Appropriate Ligand Interaction...